Anti-MTBP [2C1G6] | Ximbio 152835 product information

product summary

company name :

Ximbio

product type :

antibody

product name :

Anti-MTBP [2C1G6]

catalog :

152835

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

27085

reactivity :

human, mouse

application :

western blot

more info or order :

Ximbio product webpage

product information

Name :

Anti-MTBP [2C1G6]

Catalogue Number :

152835

Applications :

Antigen/Gene or Protein Targets :

MTBP

Synonyms :

MDM2 Binding Protein, MDM2 (Mouse Double Minute 2)-Binding Protein, Mdm2, Transformed 3T3 Cell Double Minute 2, P53 Binding Protein (Mouse) Binding Protein, Mdm2, Transformed 3T3 Cell Double Minute 2, P53 Binding Protein Binding Protein, MDM2BP, HMTBP

Reactivity :

Human and Mouse

Relevance :

MTBP is an MDM2 binding protein that alters p53/MDM2 homeostasis and may contribute to metastatic suppression. Recent studies have demonstrated that loss of MTBP expression in samples that are p53 positive and have low MDM2 is significantly associated with reduced patient survival in Squamous cell carcinoma of the head and neck (SCCHN).

Host :

Mouse

Immunogen :

Recombinant full-length human MTBP

Research Area :

Cancer, Cell Cycle, Epigenetics & Nuclear Signalling

Notes :

Clone also known as 15 or T15.

more info or order :

Ximbio product webpage