Anti-BRCA1 [24 E6] | Ximbio 152833 product information

product summary

company name :

Ximbio

product type :

antibody

product name :

Anti-BRCA1 [24 E6]

catalog :

152833

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

672

reactivity :

human

application :

western blot, immunohistochemistry

more info or order :

Ximbio product webpage

product information

Name :

Anti-BRCA1 [24 E6]

Catalogue Number :

152833

Applications :

IHC WB

Antigen/Gene or Protein Targets :

BRCA1

Synonyms :

BRCA1/BRCA2 containing complex subunit 1, BRCA1/BRCA2-containing complex, subunit 1, IRIS, PNCA4, PPP1R53, Protein phosphatase

Reactivity :

Human

Relevance :

E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain genomic stability. Regulates centrosomal microtubule nucleation. Required for normal cell cycle progression from G2 to mitosis.

Host :

Mouse

Immunogen :

Recombinant protein - aa1600-1749

Subclass :

Not Known

Research Area :

Cancer, Cell Cycle, Drug Discovery & Development, Protein Degradation

Notes :

Antibody also known as "MU

more info or order :

Ximbio product webpage