product summary
company name :
Ximbio
product type :
antibody
product name :
Anti-Erythrocyte [34-3C]
catalog :
152808
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
34-3C
reactivity :
human, mouse
application :
immunocytochemistry
more info or order :
Ximbio product webpage
product information
Name :
Anti-Erythrocyte [34-3C]
Catalogue Number :
152808
Applications :
IF Fn
Antigen/Gene or Protein Targets :
Erythrocytes
Reactivity :
Mouse
Relevance :
Anti-Erythrocyte [34-3C] is a monoclonal autoantibody-secreting hybridoma established from unmanipulated autoimmune-prone NZB mice. The antibody efficiently binds to Fc receptors on macrophages inducing anemia in vivo due to a rapid Fc receptor (FcyR)-mediated erythrophagocytosis of opsonised RBC in spleen and livers. The capacity of the antibody to interact with FcyR is responsible for its haemolytic activity.
Host :
Mouse
Immunogen :
Mouse erythrocytes
Subclass :
IgG2a
Research Area :
Immunology
Notes :
Useful for establishing in vivo model of haemolytic anaemia.
more info or order :
Ximbio product webpage
company information
Ximbio
enquiries@ximbio.com
ximbio.com