Anti-PDL2 (soluble form) [Z64P2D3*H4] | Ximbio 152795 product information

product summary

company name :

Ximbio

product type :

antibody

product name :

Anti-PDL2 (soluble form) [Z64P2D3*H4]

catalog :

152795

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

2675

reactivity :

human

application :

western blot, ELISA, immunohistochemistry

more info or order :

Ximbio product webpage

product information

Name :

Anti-PDL2 (soluble form) [Z64P2D3*H4]

Catalogue Number :

152795

Applications :

ELISA IHC WB

Antigen/Gene or Protein Targets :

Programmed Cell Death 1 Ligand 2 (PDL2-Soluble form)

Synonyms :

B7 dendritic cell molecule, B7-DC, B7DC, bA574F11.2, Btdc, Butyrophilin B7 DC, Butyrophilin B7-DC, Butyrophilin B7DC, CD 273, CD273, CD273 antigen, MGC142238, MGC142240, PD 1 ligand 2, PD L2, PD-1 ligand 2, PD-L2, PD1 ligand 2, PD1L2_HUMAN, PDCD 1 ligand 2, PDCD1 ligand 2

Reactivity :

Human

Relevance :

PDL2 is involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production. PD-1, is a key immune checkpoint. Currently several anti-PD-1 antibodies or blockers are in cancer clinical trials and showing promising outcomes. This antibody will allow scientists examine, for the first time, the clinical significance of PDL2-secreted form.

Host :

Mouse

Immunogen :

Ovalbumin-conjugated synthetic peptide KAVFFKRHN

Subclass :

Not Known

Positive Control :

IHC: formalin-fixed, paraffin-embedded multi tumour tissue microarray

Myeloma Used :

P3X63Ag8.653

Strain :

Balb/c

Research Area :

Immunology

Notes :

For IHC perform antigen retrieval step: microwave 20 min @ 800W in 10 mM citrate buffer, pH 6.0

more info or order :

Ximbio product webpage