Anti-SLA2 [Z30P1F12*F4] | Ximbio 152758 product information

product summary

company name :

Ximbio

product type :

antibody

product name :

Anti-SLA2 [Z30P1F12*F4]

catalog :

152758

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

3899

reactivity :

human

application :

western blot, ELISA, immunohistochemistry

more info or order :

Ximbio product webpage

product information

Name :

Anti-SLA2 [Z30P1F12*F4]

Catalogue Number :

152758

Applications :

ELISA IHC WB

Antigen/Gene or Protein Targets :

Src-Like-Adaptor 2 (SLA2)

Synonyms :

Modulator of antigen receptor signaling (MARS), Src-like adapter protein 2 (SLAP-2), SLA-2

Reactivity :

Human

Relevance :

SLA2 (Src-like-adapter 2), also known as C20orf156 or SLAP2, is a 261 amino acid protein that exists as four alternatively spliced isoforms which localize to either the cytoplasm or to the cell membrane and contain one SH2 domain and one SH3 domain. Expressed predominately in tissues of the immune system, including thymus, spleen and lymph nodes, SLA2 functions as an adaptor protein that negatively regulates T-cell receptor (TCR) signaling and may inhibit T-cell activation. SLA2 interacts with Zap-70 and is subject to posttranslational phosphorylation. The gene encoding SLA2 maps to human chromosome 20. Comprising approximately 2% of the human genome, chromosome 20 contains nearly 63 million bases that encode over 600 genes, some of which are associated with Creutzfeldt-Jakob disease, amyotrophic lateral sclerosis, spinal muscular atrophy, ring chromosome 20 epilepsy syndrome and Alagille syndrome.

Host :

Mouse

Immunogen :

Peptide Sequence – LRESLSFY

Subclass :

IgG

Positive Control :

Jurkat cell lysate

Molecular Weight (kDa) :

Myeloma Used :

P3X63Ag8.653

Strain :

Balb/c

Research Area :

Immunology

more info or order :

Ximbio product webpage