Anti-PAT4 [PAT4/157/D10] | Ximbio 152744 product information

product summary

company name :

Ximbio

product type :

antibody

product name :

Anti-PAT4 [PAT4/157/D10]

catalog :

152744

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

120103

reactivity :

human

application :

western blot, ELISA, immunohistochemistry

more info or order :

Ximbio product webpage

product information

Name :

Anti-PAT4 [PAT4/157/D10]

Catalogue Number :

152744

Applications :

ELISA IHC WB

Antigen/Gene or Protein Targets :

PAT4 (SLC36A4)

Reactivity :

Human

Relevance :

The anti-PAT4 [PAT-4/157/D10] antibody is a highly specific mouse monoclonal antibody against PAT4. Members of the proton-assisted amino-acid transporter (PAT) or solute-linked carrier 36 (SLC36) family have been identified as positive regulators of growth and mTORC1 signalling in flies.These effects were shown to be conserved by characterisation of the two ubiquitously transcribed human PATs, PAT1 (SLC36A1) and PAT4 (SLC36A4). PAT4 is upregulated in aggressive forms of colorectal cancer and a possible biomarker.

Host :

Mouse

Immunogen :

Antigenic amino acid sequence within the N-terminus of PAT4 (REELDMDVMRPLINE-C).

Subclass :

IgG1

Positive Control :

786-O human renal cancer cells

Molecular Weight (kDa) :

Approx 60

Myeloma Used :

NS0

Recommended Growing Conditions :

RPMI 10% FCS plus HAT essential

Research Area :

Cell Signaling & Signal Transduction, Metabolism

Notes :

A monoclonal antibody against PAT4 was created by immunising mice with a keyhole limpet haemocyanin-conjugated, cysteine-coupled peptide (Severn Biotech Ltd., Kidderminster, UK) based on an antigenic amino-acid sequence within the N terminus of PAT4 (REELDMDVMRPLINE-C).

more info or order :

Ximbio product webpage