product summary
company name :
Ximbio
product type :
antibody
product name :
Anti-VTN2 [1A5]
catalog :
152667
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
8517
reactivity :
human, zebrafish
application :
western blot, immunocytochemistry
more info or order :
Ximbio product webpage
product information
Name :
Anti-VTN2 [1A5]
Catalogue Number :
152667
Applications :
IF WB
Antigen/Gene or Protein Targets :
Splice variant of Zebrafish IKKg protein (154 amino acids)
Reactivity :
Human and Zebrafish
Relevance :
NF-?B (nuclear factor kappaB) is a transcription factor that activates numerous target genes important in mediating innate and adaptive immunity in mammals. Activation by external stimuli such as TNF leads to the activation of kinases (IKK1 and IKK2) that phosphorylate inhibitory proteins I-?B and their subsequent degradation. IKK1 and IKK2 form the catalytic subunits of a complex which includes IKK?, the regulatory component (also known as NEMO). Mutations in NEMO are the cause of the human disorders incontinentia pigmenti and ectodermal dysplasia (ED-AID).
Host :
Mouse
Immunogen :
GST/His-tagged splice variant of Zebrafish IKK? protein of 154 amino acids fusion protein
Subclass :
IgG1
Positive Control :
Zebrafish embryos, HEK293 cells
Myeloma Used :
Sp2/0-Ag14
Research Area :
Aquaculture, Epigenetics & Nuclear Signalling, Protein Degradation
more info or order :
Ximbio product webpage
company information
Ximbio
enquiries@ximbio.com
ximbio.com