product summary
company name :
Ximbio
product type :
antibody
product name :
Anti-LYPD3 [11F1]
catalog :
152660
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
11153
reactivity :
human
application :
immunocytochemistry, FACS
more info or order :
Ximbio product webpage
product information
Name :
Anti-LYPD3 [11F1]
Catalogue Number :
152660
Applications :
FACS IF
Antigen/Gene or Protein Targets :
Ly6/PLAUR domain-containing protein 3
Reactivity :
Human
Relevance :
LYPD3 (Ly6/PLAUR domain-containing protein 3) also known as C4.4A, is a structural homologue of the urokinase receptor, uPAR, which constitutes a well-established prognostic marker in various human cancers. It consists of 346 amino acids and is glycosylphosphatidylinositol (GPI)-anchored, and its extracellular domains are composed of two modules belonging to the Ly6/uPAR/?-neurotoxin (LU) protein domain family. LYPD3 is endogenously expressed in suprabasal cells of squamous epithelia and amnion membrane in human placenta. Currently, LYPD3 has no defined functions but inhibition of tumor cell migration with anti-LYPD3 antibody suggests its role in cell/cell, cell/matrix interaction and tumour invasion and metastasis.
Host :
Mouse
Immunogen :
GST-LYPD3 (residues 31 to 326) fusion protein
Subclass :
IgG1
Myeloma Used :
Sp2/0-Ag14
Research Area :
Cancer
more info or order :
Ximbio product webpage
company information
Ximbio
enquiries@ximbio.com
ximbio.com