product summary
company name :
Ximbio
product type :
antibody
product name :
Anti-CXCL16 [4.4]
catalog :
152659
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
6360
reactivity :
human
application :
western blot, immunocytochemistry
more info or order :
product information
Name :
Anti-CXCL16 [4.4]
Catalogue Number :
152659
Applications :
IF WB
Antigen/Gene or Protein Targets :
C-X-C motif chemokine 16
Reactivity :
Human
Relevance :
CXCL16, a newly discovered CXC chemokine, exists both in a transmembrane and a soluble form. The membrane bound chemokine act as a ligand for CXC chemokine receptor (CXCR) 6 which is expressed by peripheral blood leukocytes. This membrane-bound CXCL16 is expressed in antigen-presenting cells such as monocytes, macrophages, B cells and dendritic cells in the T-cell zone of lymph nodes, whereas the soluble CXCL16 can be produced by constitutive cleavage from the cell membrane. In addition, CXCL16 expression has been associated with a number of human inflammatory diseases including rheumatoid arthritis, interstitial lung diseases, atherosclerosis, coronary artery disease and liver injury.
Host :
Mouse
Immunogen :
GST-CXCL16 (143-224aa) fusion protein
Subclass :
IgG1
Myeloma Used :
Sp2/0-Ag14
Research Area :
Cardiovascular, Immunology
more info or order :
company information
Ximbio
enquiries@ximbio.com
ximbio.com