Anti-Vamp5 [3E5] | Ximbio 152657 product information

product summary

company name :

Ximbio

product type :

antibody

product name :

Anti-Vamp5 [3E5]

catalog :

152657

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

4905

reactivity :

human

application :

western blot, immunocytochemistry

more info or order :

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product information

Name :

Anti-Vamp5 [3E5]

Catalogue Number :

152657

Applications :

IF WB

Antigen/Gene or Protein Targets :

Member of Vamp subfamily of SNAREs (Soluble NSF attachment protein receptors)

Reactivity :

Human

Relevance :

SNAREs represent a superfamily of proteins responsible for the last stage of docking and subsequent fusion in diverse intracellular membrane transport events. The Vamp subfamily of SNAREs contains 7 members (Vamp1, Vamp2, Vamp3/cellubrevin, Vamp4, Vamp5, Vamp7/Ti-Vamp, and Vamp8/endobrevin) that are distributed in various post-Golgi structures. Vamp4 and Vamp5 are distributed predominantly in the trans-Golgi network (TGN) and the plasma membrane, respectively.When C-terminally tagged with enhanced green fluorescent protein, the majority of Vamp4 and Vamp5 is correctly targeted to the TGN and plasma membrane, respectively. Swapping the N-terminal cytoplasmic region and the C-terminal membrane anchor domain between Vamp4 and Vamp5 demonstrates that the N-terminal cytoplasmic region of these two SNAREs contains the correct subcellular targeting information.

Host :

Mouse

Immunogen :

GST-mV5-II and KLH-mV5-II peptide sequences

Subclass :

IgG2a

Myeloma Used :

Sp2/0-Ag14

Research Area :

Cell Signaling & Signal Transduction

more info or order :

Ximbio product webpage