product summary
company name :
Ximbio
product type :
antibody
product name :
Anti-NSP8 [5A10]
catalog :
152646
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
5A10
application :
western blot, immunocytochemistry
more info or order :
product information
Name :
Anti-NSP8 [5A10]
Catalogue Number :
152646
Applications :
IF WB
Antigen/Gene or Protein Targets :
Non-structural protein 8 of SARS-coronavirus
Reactivity :
Virus
Relevance :
Like other known coronaviruses, SARS-CoV is an enveloped, plus-strand RNA virus that features the largest RNA genomes currently known. SARS-CoV replicase polyproteins are processed by virus-encoded proteinases, and two proteinases have been identified: a 3C-like proteinase (3CLpro) and a papain-like proteinase (PLP). The processed end products of pp1a are designated nonstructural proteins (nsp) 1 to nsp11 and those of pp1ab are designated nsp1 to nsp16. Cleavage by the viral main protease, 3CLpro results in generating the nsp8 protein which is currently of undesignated function. The nsp8 protein has been indicated to associate with several other nsps and to colocalize with these nsps in cytoplasmic complexes that are important for viral RNA synthesis.
Host :
Mouse
Immunogen :
GST-NSP8 fusion protein
Subclass :
IgG2a
Myeloma Used :
Sp2/0-Ag14
Research Area :
Virology
more info or order :
company information
Ximbio
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