Anti-MOAP-1 [4A12] | Ximbio 152644 product information

product summary

company name :

Ximbio

product type :

antibody

product name :

Anti-MOAP-1 [4A12]

catalog :

152644

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

64112

reactivity :

human

application :

western blot, immunocytochemistry

more info or order :

Ximbio product webpage

product information

Name :

Anti-MOAP-1 [4A12]

Catalogue Number :

152644

Applications :

IF WB

Antigen/Gene or Protein Targets :

Modulator of apoptosis-1

Reactivity :

Human

Relevance :

MOAP-1, also known as MAP-1 (Modulator of apoptosis-1) was initially identified as a Bax-associating protein from a yeast two-hybrid screen using Bax as bait. MOAP-1 is enriched in mitochondria and appears to be an effector for mediating Bax function in mitochondria. Moreover, in supporting the idea that MOAP-1 may be involved in a tumor suppressor axis, MOAP-1 is found to associate with the tumor suppressor RASSF1A to mediate Bax-dependent apoptosis in response to death receptor activation in tumor cells.

Host :

Mouse

Immunogen :

GST-MOAP-1 (N-terminal) fusion protein

Subclass :

IgG1

Myeloma Used :

Sp2/0-Ag14

Research Area :

Apoptosis and Programmed Cell Death, Cancer

more info or order :

Ximbio product webpage