Anti-AIF [3C11] RECENTLY UPDATED | Ximbio 152633 product information

product summary

company name :

Ximbio

product type :

antibody

product name :

Anti-AIF [3C11] RECENTLY UPDATED

catalog :

152633

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

3054

reactivity :

human

application :

western blot

more info or order :

Ximbio product webpage

product information

Name :

Anti-AIF [3C11] RECENTLY UPDATED

Catalogue Number :

152633

Applications :

Antigen/Gene or Protein Targets :

Mammalian apoptosis-inducing factor

Reactivity :

Human

Relevance :

Mammalian apoptosis-inducing factor (AIF) has been reported to be mainly found in the inter-membrane space of the mitochondria. After exposure to apoptotic stimuli, AIF is expelled as a soluble protein from the permeabilized mitochondria membrane and translocates to the nucleus, resulting in chromatin condensation and DNA cleavage. AIF mediated apoptosis is caspase-independent. AIF mutants that could not bind to DNA could not mediate cell death.

Host :

Mouse

Immunogen :

AIF-His fusion protein

Subclass :

IgG1

Myeloma Used :

Sp2/0-Ag14

Research Area :

Apoptosis and Programmed Cell Death, Cancer, Cell Cycle, Cell Type or Organelle Marker, Epigenetics & Nuclear Signalling, Metabolism

more info or order :

Ximbio product webpage