Anti-AKT1 [V7] | Ximbio 152617 product information

product summary

company name :

Ximbio

product type :

antibody

product name :

Anti-AKT1 [V7]

catalog :

152617

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

100005514

reactivity :

zebrafish

application :

western blot, ELISA, immunohistochemistry

more info or order :

Ximbio product webpage

product information

Name :

Anti-AKT1 [V7]

Catalogue Number :

152617

Applications :

ELISA IHC WB

Antigen/Gene or Protein Targets :

V-Akt Murine Thymoma Viral Oncogene Homolog 1 (AKT1)

Reactivity :

zebrafish

Relevance :

The serine-threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3-kinase. In the developing nervous system AKT is a critical mediator of growth factor-induced neuronal survival.

Host :

Mouse

Immunogen :

Ovalbumin-conjugated synthetic peptide KDPMQRLGGG (C-terminal sequence)

Subclass :

IgG2a kappa

Positive Control :

ELISA - peptide immunogen; WB - whole organism lysate; IHC - zebrafish embryo

Myeloma Used :

P3X63Ag8.653

Strain :

Balb/c

Research Area :

Aquaculture, Apoptosis and Programmed Cell Death, Cancer, Cell Cycle, Cell Signaling & Signal Transduction, Epigenetics & Nuclear Signalling, Metabolism, Neurobiology

more info or order :

Ximbio product webpage