Anti-RUNX3 [K12P3F11*C9] | Ximbio 152611 product information

product summary

company name :

Ximbio

product type :

antibody

product name :

Anti-RUNX3 [K12P3F11*C9]

catalog :

152611

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

7027

reactivity :

human

application :

western blot, ELISA, immunohistochemistry

more info or order :

Ximbio product webpage

product information

Name :

Anti-RUNX3 [K12P3F11*C9]

Catalogue Number :

152611

Applications :

ELISA IHC WB

Antigen/Gene or Protein Targets :

Runt-related transcription factor 3

Reactivity :

Human

Relevance :

Runx3 (also known as AML2 and CBF alpha 3) forms a heterodimer with a beta subunit. The complex binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Multiple transcript variants encoding different isoforms have been found for this gene.

Host :

Mouse

Immunogen :

Peptide – QFDRSFPTL

Subclass :

IgG1 kappa

Positive Control :

WB - Jurkat cell lysates; IHC- formalin-fixed, paraffin-embedded multi tumour tissue microarray

Molecular Weight (kDa) :

Myeloma Used :

P3X63Ag8.653

Research Area :

Epigenetics & Nuclear Signalling

more info or order :

Ximbio product webpage