product summary
company name :
Ximbio
product type :
antibody
product name :
Anti-sCD40 (soluble) [T8P2G4*A6]
catalog :
152605
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
6647
reactivity :
human
application :
western blot, ELISA, immunohistochemistry
more info or order :
product information
Name :
Anti-sCD40 (soluble) [T8P2G4*A6]
Catalogue Number :
152605
Applications :
ELISA IHC WB
Antigen/Gene or Protein Targets :
CD40 Molecule, TNF Receptor Superfamily Member 5 (CD40 soluble form)
Synonyms :
CD40 Molecule; CD40L Receptor; TNFRSF5; CDW40; Bp50; Tumor Necrosis Factor Receptor Superfamily; Member; B Cell Surface Antigen CD40; CD40 Antigen; P50
Reactivity :
Human
Relevance :
CD40 is a 48 kD type I glycoprotein and a member of the TNFR superfamily primarily expressed on B cells, macrophages, follicular dendritic cells, endothelial cells, fibroblasts, and at low levels on plasma cells. CD40 is also expressed on a wide range of tumor cells, including non-Hodgkin's and Hodgkin's lymphomas, myeloma and some carcinomas including nasopharynx, bladder, cervix, kidney and ovary.The binding of CD154 (CD40L) on TH cells to CD40 activates antigen presenting cells and induces a variety of downstream effects.
Host :
Mouse
Immunogen :
Ovalbumin-conjugated synthetic peptide RDPVCHPLGA (C-terminal sequence)
Subclass :
IgG1 kappa
Positive Control :
IHC - formalin-fixed, paraffin-embedded hepatocellular carcinoma sections; WB - Jurkat cell lysates
Molecular Weight (kDa) :
22
Research Area :
Cancer, Cell Signaling & Signal Transduction
more info or order :
company information
Ximbio
enquiries@ximbio.com
ximbio.com