product summary
company name :
Ximbio
product type :
antibody
product name :
Anti-Alanyl-tRNA Synthetase [M6-P2E5]
catalog :
152601
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
2224
reactivity :
human
application :
western blot, ELISA, immunohistochemistry
more info or order :
product information
Name :
Anti-Alanyl-tRNA Synthetase [M6-P2E5]
Catalogue Number :
152601
Applications :
ELISA IHC WB
Antigen/Gene or Protein Targets :
Alanyl-tRNA Synthetase (AARS)
Reactivity :
Human
Relevance :
The human alanyl-tRNA synthetase (AARS) belongs to a family of tRNA synthases, of the class II enzymes. Class II tRNA synthases evolved early in evolution and are highly conserved. This is reflected by the fact that 498 of the 968-residue polypeptide human AARS shares 41% identity with the E.coli protein. tRNA synthases are the enzymes that interpret the RNA code and attach specific amino acids to the tRNAs that contain the cognate trinucleotide anticodons. They consist of a catalytic domain which interacts with the amino acid acceptor-T psi C helix of the tRNA, and a second domain which interacts with the rest of the tRNA structure.
Host :
Mouse
Immunogen :
Peptide – TSFAQLRLGD (amino acid 956-965)
Subclass :
IgG1 kappa
Positive Control :
Western Blot - Hela cell lysates; IHC - Human breast cancer tissue
Molecular Weight (kDa) :
110
Research Area :
Epigenetics & Nuclear Signalling
Notes :
Please note for IHC antigen retrieval is required: ,icrowave 20 min @ 800W in 10 mM citrate buffer, pH 6.0
more info or order :
company information
Ximbio
enquiries@ximbio.com
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