product summary
company name :
Ximbio
product type :
antibody
product name :
Anti-Cytochrome P450 27A1 [V29-P4B8*B2]
catalog :
152599
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
1593
reactivity :
human
application :
western blot, ELISA, immunohistochemistry
more info or order :
product information
Name :
Anti-Cytochrome P450 27A1 [V29-P4B8*B2]
Catalogue Number :
152599
Applications :
ELISA IHC WB
Antigen/Gene or Protein Targets :
Cytochrome P450, Family 27, Subfamily A, Polypeptide 1 (CYP27A1), Sterol 27-Hydroxylase
Reactivity :
Human
Relevance :
Cytochrome P450 27A1 (CYP27A1) catalyzes the first step in the oxidation of the side chain of sterol intermediates; the 27-hydroxylation of 5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol. Has also a vitamin D3-25-hydroxylase activity.
Host :
Mouse
Immunogen :
Ovalbumin-conjugated synthetic peptide KVVLAPETGEL (C-terminal sequence)
Subclass :
IgG1 kappa
Positive Control :
IHC: formalin-fixed, paraffin-embedded human sections; WB: Overexpression lysates
Research Area :
Cancer, Cardiovascular, Cell Signaling & Signal Transduction, Metabolism
Notes :
For IHC perform antigen retrieval: microwave 20 min @ 800W in 10 mM citrate buffer, pH 6.0 This antibody was applied in a poster presented at the 2015 NCRI conference: http://abstracts.ncri.org.uk/?s=oxysterol&year_published=2015
more info or order :
company information
Ximbio
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