product summary
company name :
Ximbio
product type :
antibody
product name :
Anti-CD3, Recombinant [UCH-T1®]
catalog :
152589
clonality :
polyclonal
host :
mouse
conjugate :
nonconjugated
clone name :
912
reactivity :
human
application :
western blot, FACS
more info or order :
Ximbio product webpage
product information
Name :
Anti-CD3, Recombinant [UCH-T1®]
Catalogue Number :
152589
Applications :
FACS WB
Antigen/Gene or Protein Targets :
CD3
Reactivity :
Human
Relevance :
The CD3 complex, composed of five CD3 polypeptide chains, associates with the T cell antigen receptor (TCR) and is found on all mature human T lymphocytes. UCH-T1/UCHT1 is considered a pan T-cell marker - it can be used for the detection of T cell populations in peripheral blood and lymph nodes and the categorisation of T versus B cell lymphomas and leukaemias. It reacts with the majority of peripheral blood T lymphocytes, a major proportion of thymocytes, the majority of T cell chronic lymphocytic leukaemia cells, Sézary leukaemias and approximately 70% of acute lymphoblastic leukaemias of T cell origin. It can also be used to study the role of CD3 in TCR signal transduction events.
Host :
Mouse
Immunogen :
Human infant thymocytes and Sezary cells.
Subclass :
IgG1
Research Area :
Cancer, Cell Type or Organelle Marker, Cell Signaling & Signal Transduction, Immunology, Stem Cell Biology
Notes :
Recommended for the enrichment of T cell populations by cell sorting or panning. Recombinant monoclonal antibody produced from the original monoclonal. Manufactured using Absolute Antibody’s Recombinant Platform with variable regions (i.e. specificity) from the hybridoma.
Formulation :
PBS only
Concentration :
1mg/ml
more info or order :
Ximbio product webpage
company information
Ximbio
enquiries@ximbio.com
ximbio.com