Anti-FIKK4.2 [126] | Ximbio 152528 product information

product summary

company name :

Ximbio

product type :

antibody

product name :

Anti-FIKK4.2 [126]

catalog :

152528

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

126

reactivity :

human

more info or order :

Ximbio product webpage

product information

Name :

Anti-FIKK4.2 [126]

Catalogue Number :

152528

Antigen/Gene or Protein Targets :

FIKK4.2

Reactivity :

Plasmodium

Relevance :

Monoclonal antibody to the R45 antigen, now known as FIKK4.2 and putative exported kinase of Plasmodium falciparum. A unique family of parasite putative exported kinases, collectively called FIKK (Phenylalanine (F) – Isoleucine (I) – Lysine (K) – Lysine (K)), has recently been implicated in the adhesive and mechanical properties of red blood cells caused by infection with the malaria parasite Plasmodium falciparum. FIKK4.2, one member of the FIKK family, can function as an active kinase and is localised in a novel and distinct compartment of the parasite-infected red blood cell; disruption of the gene encoding FIKK4.2 (fikk4.2) dramatically alters the parasite’s ability to modify and remodel the red blood cells in which it multiplies.

Host :

Mouse

Subclass :

IgG1 kappa

Research Area :

Adhesion, Cardiovascular, Parasitology

Notes :

UK Biosafety level: 1

more info or order :

Ximbio product webpage