Anti-Pfs 48/45 [3E12] | Ximbio 152525 product information

product summary

company name :

Ximbio

product type :

antibody

product name :

Anti-Pfs 48/45 [3E12]

catalog :

152525

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

3E12

more info or order :

Ximbio product webpage

product information

Name :

Anti-Pfs 48/45 [3E12]

Catalogue Number :

152525

Antigen/Gene or Protein Targets :

Pfs 48/45

Reactivity :

Plasmodium

Relevance :

Fertilization and zygote development are obligate features of the malaria parasite life cycle and occur during parasite transmission to mosquitoes. The surface protein PFS48/45 is expressed by male and female gametes of Plasmodium falciparum and PFS48/45 antibodies prevent zygote development and transmission. Pfs 48/45 is therefore a good target antigen of malaria transmission blocking antibodies.

Host :

Mouse

Immunogen :

Gametocytes of the 7G8 isolate of P. falciparum.

Subclass :

IgG1

Myeloma Used :

P3/NS1/1-Ag4.1

Strain :

Balb/c

Research Area :

Parasitology

Notes :

Recognises the P. falciparum Pfs 48/45 antigen expressed on gametocytes of P. falciparum. Inhibitory in mosquito membrane feeding assays. UK Biosafety level: 1

more info or order :

Ximbio product webpage