product summary
company name :
Ximbio
product type :
antibody
product name :
Anti-RAP-1 [2.29]
catalog :
152524
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
2.29
reactivity :
human
more info or order :
product information
Name :
Anti-RAP-1 [2.29]
Catalogue Number :
152524
Antigen/Gene or Protein Targets :
RAP1
Reactivity :
Plasmodium
Relevance :
In considering methods for immunological control of Plasmodium falciparum malaria it is essential to know more about antigenic diversity within and between natural populations of the parasite from major endemic areas. A successful malaria vaccine would stimulate an individual's immune system to respond to the malaria parasite and prevent serious clinical disease. Many different groups are currently developing potential vaccines. Rhoptry associated protein 1 (RAP1) and 2 (RAP2), together with a poorly described third protein RAP3, form the low molecular weight complex within the rhoptries of Plasmodium falciparum. These proteins are thought to play a role in erythrocyte invasion by the extracellular merozoite and are important vaccine candidates.
Host :
Mouse
Immunogen :
Schizonts from the K1 isolate of P. falciparum
Subclass :
IgG1
Myeloma Used :
P3/NS1/1-Ag4.1
Strain :
Balb/c
Research Area :
Cell Type or Organelle Marker, Epigenetics & Nuclear Signalling, Parasitology
Notes :
Recognises rhoptry-associated protein 1 (RAP1) of P. falciparum. UK Biosafety level: 1
more info or order :
company information
Ximbio
enquiries@ximbio.com
ximbio.com