Anti-GAPDH [7.2] | Ximbio 152516 product information

product summary

company name :

Ximbio

product type :

antibody

product name :

Anti-GAPDH [7.2]

catalog :

152516

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

7.2

reactivity :

human

more info or order :

Ximbio product webpage

product information

Name :

Anti-GAPDH [7.2]

Catalogue Number :

152516

Antigen/Gene or Protein Targets :

GAPDH

Reactivity :

Plasmodium

Relevance :

GAPDH is a pivotal enzyme in the glycolytic pathway. It uses NAD+ to catalyze the reversible oxidative phosphorylation of glyceraldehyde-3-phosphate to 1,3-diphosphoglycerate, thereby generating reducing equivalents. In addition, GAPDH is thought to be involved in a variety of other cellular activities. These include putative roles in membrane fusion, tubulin bundling, phosphotransferase activity, nuclear RNA transport, and DNA replication and repair. Given the central role of this protein, plasmodial GAPDH appears to be a vulnerable target within the metabolism of the parasite.

Host :

Mouse

Immunogen :

Schizont extracts

Subclass :

IgG1

Research Area :

Cancer, Cell Signaling & Signal Transduction, DNA Damage and Repair, Metabolism, Neurobiology, Parasitology

Notes :

Recognises P. falciparum GAPDH. May also recognise other Plasmodium spp. GAPDH UK Biosafety level: 1

more info or order :

Ximbio product webpage