Anti-MSP1 Block 4b [12.1] | Ximbio 152507 product information

product summary

company name :

Ximbio

product type :

antibody

product name :

Anti-MSP1 Block 4b [12.1]

catalog :

152507

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

12.1

reactivity :

human

more info or order :

Ximbio product webpage

product information

Name :

Anti-MSP1 Block 4b [12.1]

Catalogue Number :

152507

Antigen/Gene or Protein Targets :

MSP-1 Block 4 (MAD20)

Reactivity :

Plasmodium

Relevance :

In considering methods for immunological control of Plasmodium falciparum malaria it is essential to know more about antigenic diversity within and between natural populations of the parasite from major endemic areas. A successful malaria vaccine would stimulate an individual's immune system to respond to the malaria parasite and prevent serious clinical disease. Many different groups are currently developing potential vaccines. Several candidates are based on a protein called MSP1 (merozoite surface protein 1) which is found on the surface of the blood stage form of the malaria parasite.

Host :

Mouse

Immunogen :

Schizont extracts

Subclass :

IgG1

Myeloma Used :

P3/NS1/1-Ag4.1

Research Area :

Parasitology

Notes :

Recognises MSP-1 Block 4, C-terminal half, with the epitope sequence 334-PLPENKKKEVEG-345. This sequence is found in the MAD20 isolate. See Miller et al., 1993 Mol. Biochem. Parasitol. 59:1-14 for details of MSP-1 sequence variation UK Biosafety level: 1

more info or order :

Ximbio product webpage