product summary
company name :
Ximbio
product type :
antibody
product name :
Anti-Pfs48/45 [3G12]
catalog :
152491
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
3G12
more info or order :
product information
Name :
Anti-Pfs48/45 [3G12]
Catalogue Number :
152491
Antigen/Gene or Protein Targets :
Surface protein Pfs48/45
Reactivity :
Plasmodium
Relevance :
Fertilization and zygote development are obligate features of the malaria parasite life cycle and occur during parasite transmission to mosquitoes. The surface protein PFS48/45 is expressed by male and female gametes of Plasmodium falciparum and PFS48/45 antibodies prevent zygote development and transmission. Pfs 48/45 is therefore a good target antigen of malaria transmission blocking antibodies.
Host :
Mouse
Immunogen :
Gametocytes of the 7G8 isolate (Plasmodium falciparum isolated from a 12 year old male from Manaus, Brazil on 12th March 1980 by Dr. K.M. McNeil)
Subclass :
IgG1
Myeloma Used :
P3/NS1/1-Ag4.1
Research Area :
Parasitology
Notes :
UK Biosafety level: 1 Recognises an epitope of P. falciparum Pfs48/45. Non-inhibitory in mosquito membrane feeding assays.
more info or order :
company information
Ximbio
enquiries@ximbio.com
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