product summary
company name :
Ximbio
product type :
antibody
product name :
Anti-CD151 [11G5a]
catalog :
152484
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
977
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, FACS
more info or order :
Ximbio product webpage
product information
Name :
Anti-CD151 [11G5a]
Catalogue Number :
152484
Applications :
ELISA FACS IHC IF IP WB
Antigen/Gene or Protein Targets :
CD151 (PETA-3)
Synonyms :
CD151 Molecule (Raph Blood Group); Platelet-Endothelial Tetraspan Antigen; CD151 Antigen (Raph Blood Group); Membrane Glycoprotein SFA-1; Tetraspanin-24; CD151 Antigen; Tspan-24; TSPAN24; PETA-3
Reactivity :
Human
Relevance :
Clone 11G5a recognizes the human CD151 cell surface antigen, also known as PETA-3. CD151 is expressed by epithelial cells, endothelial cells, platelets, megakaryocytes, monocytes and in the renal glomeruli and proximal and distal tubules. CD151 is not expressed by lymphocytes or granulocytes. More recently CD151 has also been shown to be expressed by erythrocytes, and to carry the MER2 blood group antigen. CD151 is a cell surface glycoprote involved in cellular processes including cell adhesion and may regulate integrin trafficking and/or function. This protein enhances cell motility, invasion and metastasis of cancer cells.
Host :
Mouse
Subclass :
IgG1
Positive Control :
Tonsil/spleen.
Myeloma Used :
P3X63Ag8.653
Research Area :
Adhesion, Cancer, Cardiovascular, Cell Signaling & Signal Transduction, Cell Structure and Motility
Notes :
CD151 is very closely associated with the alpha3 beta1 integrin in cells and co-immunoprecipitation may occur even in quite stringent conditions (Yauch. et al. 1998). For staining of paraffin section antigen retrieval through heat treatment with Sodium citrate buffer pH 6.0 is recommended.
more info or order :
Ximbio product webpage
company information
Ximbio
enquiries@ximbio.com
ximbio.com