product summary
company name :
Ximbio
product type :
antibody
product name :
Anti-CD49b [16B4]
catalog :
152483
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
3655
reactivity :
human
application :
ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, FACS
more info or order :
Ximbio product webpage
product information
Name :
Anti-CD49b [16B4]
Catalogue Number :
152483
Applications :
ELISA FACS IHC IF IP
Antigen/Gene or Protein Targets :
CD49f (Integrin a2+b1)
Synonyms :
Integrin Subunit Alpha 2; Alpha 2 Subunit Of VLA-2 Receptor; Platelet Membrane Glycoprotein Ia; CD49 Antigen-Like Family Member B; Collagen Receptor; CD49B; GPIa; Very Late Activation Protein 2 Receptor; Alpha-2 Subunit; Human Platelet Alloantigen System; Platelet Glycoprotein GPIa; VLA-2 Subunit Alpha; CD49b Antigen; HPA-5; VLA-2; VLAA2; BR
Reactivity :
Human
Relevance :
CD49b is an integrin alpha subunit which makes up half of the ?2?1 integrin duplex. Integrins are heterodimeric integral membrane glycoproteins composed of a distinct alpha chain and a common beta chain. They are found on a wide variety of cell types including, T cells (the NKT cells), NK cells, fibroblasts and platelets. Integrins are involved in cell adhesion and also participate in cell-surface mediated signalling.
Host :
Mouse
Immunogen :
Purified human beta 1 preparation from HT1080 fibrosarcoma cell extract.
Subclass :
IgG1
Positive Control :
In IF, this antibody gave a positive signal in HepG2 cells.
Myeloma Used :
P3X63Ag8.653
Research Area :
Adhesion, Cell Signaling & Signal Transduction, Immunology
Notes :
16B4 can be used to immunoprecipitate a non-reducible alpha subunit from I(125) surface labelled Human cell line extract. It is specific to the alpha 2 subunit by relative expression of antigen on various cell lines by FACS, and its recognition of affinity purified alpha 2 beta 1 in dot blots.
more info or order :
Ximbio product webpage
company information
Ximbio
enquiries@ximbio.com
ximbio.com