Anti-DDR1 [3H10] | Ximbio 152441 product information

product summary

company name :

Ximbio

product type :

antibody

product name :

Anti-DDR1 [3H10]

catalog :

152441

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

780

reactivity :

human

application :

immunohistochemistry, immunocytochemistry, immunoprecipitation, FACS

more info or order :

Ximbio product webpage

product information

Name :

Anti-DDR1 [3H10]

Catalogue Number :

152441

Applications :

FACS IHC IF IP

Antigen/Gene or Protein Targets :

Extracellular region of DDR1

Synonyms :

Discoidin Domain Receptor Tyrosine Kinase; CD167 Antigen-Like Family Member A; Protein-Tyrosine Kinase RTK-6; Mammary Carcinoma Kinase 10; Tyrosine-Protein Kinase CAK; Cell Adhesion Kinase; Tyrosine Kinase DDR; EDDR1; NTRK4; PTK3A; HGK2; RTK6; TRKE; CAK; NEP; Neurotrophic Tyrosine Kinase; Receptor Type 4; Discoidin Domain Receptor Family; Member; Epithelial Discoidin Domain Receptor; Discoidin Receptor Tyrosine Kinase; PTK3A Protein Tyrosine Kinase 3A; Neuroepithelial Tyrosine Kinase; Protein-Tyrosine Kinase 3A; CD167a Antigen; MCK10; TRK E; PTK3; DDR

Reactivity :

Human

Relevance :

The discoidin domain receptor tyrosine kinase DDR1 (CD167a) is activated by phosphorilation upon binding to the extracellular matrix collagen. It is involved in cellular regulatory processes involving cell growth, differentiation and metabolism; alterations of its activity have been linked to several human diseases including cancer.

Host :

Mouse

Immunogen :

Recombinant protein produced in HEK293 cells encompassing the entire ectodomain of human DDR1

Subclass :

IgG1

Positive Control :

HEK293

Recommended Growing Conditions :

37°C, 5% CO2 in RPMI-1640 + 10% FBS, 1 mM sodium pyruvate, 10 U/ml penicillin, 100 ?g/ml streptomycin, 1 ?g/ml fungizone

Strain :

Balb/c

Research Area :

Cancer, Cardiovascular, Cell Signaling & Signal Transduction, Metabolism, Neurobiology

Notes :

Not suitable for WB Inhibits collagen-induced DDR1 phosphorylation as mAb or Fab withouth disrupting binding of collagen

more info or order :

Ximbio product webpage