Anti-HSV gD [AP12] | Ximbio 152408 product information

product summary

company name :

Ximbio

product type :

antibody

product name :

Anti-HSV gD [AP12]

catalog :

152408

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

AP12

application :

immunohistochemistry, immunocytochemistry, immunoprecipitation

more info or order :

Ximbio product webpage

product information

Name :

Anti-HSV gD [AP12]

Catalogue Number :

152408

Applications :

IHC IF IP

Antigen/Gene or Protein Targets :

Herpes Simplex Virus Glycoprotein D (HSV gD)

Reactivity :

Virus

Relevance :

The envelope of herpes simplex virus (HSV) is complex, as it contains at least 10 virus-encoded glycoproteins. However, only a subset of these mediate virus entry in cell culture. The initial interaction of HSV with cell surface heparan sulfate proteoglycans is mediated by glycoprotein C (gC) and/or gB. This is presumably followed by interaction of one or more of the viral glycoproteins with cellular receptors. Then gD, gB, and the complex of gH and gL act individually or in combination to trigger pH-independent fusion of the viral envelope with the host cell plasma membrane

Host :

Mouse

Subclass :

IgG1

Research Area :

Virology

Notes :

Works well for immunofluorescence (IF) on fixed specimens and for immunoprecipitiation (IP) on triton solubilised samples. Does not work in Western blots. The antibody epitope is well characterised by binding competition assays and by sequencing of antibody escape mutants.

more info or order :

Ximbio product webpage