Anti-CD45R [YTH 80.103] | Ximbio 152401 product information

product summary

company name :

Ximbio

product type :

antibody

product name :

Anti-CD45R [YTH 80.103]

catalog :

152401

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

5788

reactivity :

human

application :

immunohistochemistry, FACS

more info or order :

Ximbio product webpage

product information

Name :

Anti-CD45R [YTH 80.103]

Catalogue Number :

152401

Applications :

FACS IHC

Antigen/Gene or Protein Targets :

Human CD45R

Synonyms :

Protein Tyrosine Phosphatase; Receptor Type C; CD45 Antigen; CD45; L-CA; T200; Protein Tyrosine Phosphatase; Receptor Type; C Polypeptide; T200 Leukocyte Common Antigen; T200 Glycoprotein; EC 3.1.3.48; GP180; CD45R; B220; LCA; LY5

Reactivity :

Human

Relevance :

CD45R, also known as B220, is an isoform of CD45. It is a member of the protein tyrosine phosphatase (PTP) family with a molecular weight of approximately 180-240 kD. CD45R is expressed on B cells (at all developmental stages from pro-B cells through mature B cells), activated B cells, and subsets of T and NK cells. CD45R (B220) is also expressed on a subset of abnormal T cells involved in the pathogenesis of systemic autoimmunity in MRL-Faslpr and MRL-Fasgld mice. It plays a critical role in TCR and BCR signaling. The primary ligands for CD45 are galectin-1, CD2, CD3, and CD4. CD45R is commonly used as a pan-B cell marker; however, CD19 may be more appropriate for B cell specificity.

Host :

Mouse

Subclass :

IgG2b

Research Area :

Cancer, Cell Type or Organelle Marker, Cell Signaling & Signal Transduction, Immunology, Stem Cell Biology

more info or order :

Ximbio product webpage