Anti-Tie-2R [3G1] | Ximbio 152395 product information

product summary

company name :

Ximbio

product type :

antibody

product name :

Anti-Tie-2R [3G1]

catalog :

152395

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

21846

reactivity :

mouse

application :

western blot, ELISA, immunoprecipitation, FACS

more info or order :

Ximbio product webpage

product information

Name :

Anti-Tie-2R [3G1]

Catalogue Number :

152395

Applications :

ELISA FACS IP WB

Antigen/Gene or Protein Targets :

Tie-2R

Synonyms :

TEK Receptor Tyrosine Kinase; Tyrosine Kinase With Ig And EGF Homology Domains-2; Tunica Interna Endothelial Cell Kinase; Tyrosine-Protein Kinase Receptor TIE-2; Endothelial Tyrosine Kinase; VMCM1; TIE2; Venous Malformations; Multiple Cutaneous And Mucosal; CD202b Antigen; P140 TEK; CD202B; TIE-2; HTIE2

Reactivity :

Mouse

Relevance :

Tie-2 is a 145 kD type I transmembrane protein, also known as CD202b or TEK. It is a member of the receptor tyrosine kinase (RTK) family of proteins and is expressed by endothelial cells and their progenitors, quiescent hematopoietic stem cells (HSCs), and a subpopulation of monocytes. Angiopoietin-1 (Ang-1) is an activator of Tie-2 to promote, maintain, and stabilize mature vessels and to maintain HSCs in quiescent state. Ang-2 is another ligand of Tie-2, which is involved in postnatal angiogenesis and in antagonizing the effects of Ang-1. Tie-2 binds to Ang-4 as well.

Host :

Rat

Subclass :

IgG1

Research Area :

Cancer, Cardiovascular, Cell Type or Organelle Marker, Cell Signaling & Signal Transduction, Developmental Biology, Stem Cell Biology

more info or order :

Ximbio product webpage