Anti-PDGFR [PDGFR-B2] | Ximbio 152389 product information

product summary

company name :

Ximbio

product type :

antibody

product name :

Anti-PDGFR [PDGFR-B2]

catalog :

152389

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

5159

reactivity :

human

application :

immunocytochemistry, immunoprecipitation

more info or order :

Ximbio product webpage

product information

Name :

Anti-PDGFR [PDGFR-B2]

Catalogue Number :

152389

Applications :

IF IP

Antigen/Gene or Protein Targets :

PDGFR

Reactivity :

Human and Pig

Relevance :

This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies in knockout mice, where homozygosity is lethal, indicate that the alpha form of the platelet-derived growth factor receptor is particularly important for kidney development since mice heterozygous for the receptor exhibit defective kidney phenotypes.

Host :

Mouse

Subclass :

IgG2b

Myeloma Used :

P3X63Ag8.653

Research Area :

Cancer

more info or order :

Ximbio product webpage