Anti-p27 [SX18F7] | Ximbio 152387 product information

product summary

company name :

Ximbio

product type :

antibody

product name :

Anti-p27 [SX18F7]

catalog :

152387

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

1027

reactivity :

human

application :

western blot, immunoprecipitation

more info or order :

Ximbio product webpage

product information

Name :

Anti-p27 [SX18F7]

Catalogue Number :

152387

Applications :

IP WB

Antigen/Gene or Protein Targets :

p27

Synonyms :

Cyclin-Dependent Kinase Inhibitor 1B; P27KIP1; KIP1; Cyclin-Dependent Kinase Inhibitor P27; CDKN4; MEN1B; MEN4

Reactivity :

Human

Relevance :

p27 (cyclin-dependent kinase inhibitor 1B, cyclin-dependent kinase inhibitor p27, Kip27) is a 27kD cyclin-dependent inhibitor. p27 is localized in the nucleus and cytoplasm (phospho-specific). This protein functions in G1 arrest and binds and inhibits complexes formed by cyclin E-CDK2, cyclin A-CDK2. p27Kip1 mediates TGF ?-induced G1 arrest and regulates cell motility. This kinase has also been implicated in translational control. Akt phosphorylation causes p27 Kip1 export to cytoplasm; p27 Kip1 has also been shown to be ubiquitinated. p27 Kip1 has been shown to interact with NUP50, Skp2, and PKB/Akt.

Host :

Mouse

Subclass :

IgG1 kappa

Research Area :

Cancer, Cell Cycle, Epigenetics & Nuclear Signalling

more info or order :

Ximbio product webpage