product summary
company name :
Ximbio
product type :
antibody
product name :
Anti-p21 [SXM30]
catalog :
152385
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
1026
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation
more info or order :
product information
Name :
Anti-p21 [SXM30]
Catalogue Number :
152385
Applications :
IHC IF IP WB
Antigen/Gene or Protein Targets :
p21
Synonyms :
Cyclin-Dependent Kinase Inhibitor 1A; CDK-Interacting Protein 1; CDKN1; CAP20; MDA-6; CIP1; SDI1; WAF1; P21; Melanoma Differentiation Associated Protein 6; Wild-Type P53-Activated Fragment 1; CDK-Interaction Protein 1; DNA Synthesis Inhibitor; P21CIP1; MDA6; PIC1
Reactivity :
Human, Mouse and Rat
Relevance :
p21 (Cyclin-Dependent Kinase Inhibitor 1A, CIP1) regulates cell cycle progression, terminal differentiation, and apoptosis. p21 was shown to be induced by p53 and to be a potent inhibitor of cyclin-dependent kinase (CDK) activity. DNA damage leads to increased expression of p21 in cyclin E-containing complexes and to an associated decrease in cyclin-dependent kinase activity. p21 is a critical downstream effector in the p53-specific pathway of growth control in mammalian cells.
Host :
Mouse
Subclass :
IgG1
Research Area :
Cancer, Cell Cycle, DNA Damage and Repair, Epigenetics & Nuclear Signalling
more info or order :
company information
Ximbio
enquiries@ximbio.com
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