Anti-NY-ESO-1 [E978] | Ximbio 152384 product information

product summary

company name :

Ximbio

product type :

antibody

product name :

Anti-NY-ESO-1 [E978]

catalog :

152384

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

E978

application :

ELISA

more info or order :

Ximbio product webpage

product information

Name :

Anti-NY-ESO-1 [E978]

Catalogue Number :

152384

Applications :

ELISA

Antigen/Gene or Protein Targets :

NY-ESO-1

Relevance :

Cancer/testis (CT) antigens are the protein products of genes that are activated in a wide variety of tumors and can elicit autologous cellular and humoral immune responses. Their normal expression is restricted to male germ cells in the testis and they are not expressed in adult somatic tissues. Therefore, CT antigens are promising candidates for cancer immunotherapy. Approximately 20 CT antigens or antigen families have been identified to date. NY-ESO-1 is a CT protein to which cell-mediated immune response has been demonstrated. The protein is expressed in normal testis and to a much lower extent in placenta, ovary and uterus. However, it is mainly expressed in many different cancers. The expression of genes encoding CT antigens has been found in sporadic medullary thyroid carcinoma, breast cancer especially in benign lesions and in multiple myeloma. Due to its wide expression in different cancers, NY-ESO-1 protein was used as a vaccine in cancer patients.

Host :

Mouse

Research Area :

Cancer, Cell Type or Organelle Marker

more info or order :

Ximbio product webpage