product summary
company name :
Ximbio
product type :
antibody
product name :
Anti-Notch-2 [16f11]
catalog :
152383
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
16F11
reactivity :
human
application :
immunoprecipitation, FACS
more info or order :
Ximbio product webpage
product information
Name :
Anti-Notch-2 [16f11]
Catalogue Number :
152383
Applications :
FACS IP
Antigen/Gene or Protein Targets :
Notch-2
Synonyms :
Notch 2; HN2; Notch Homolog 2; HJCYS; AGS2
Relevance :
Notch-2 is a transmembrane receptor, which contains 5 ankyrin repeats, 29-36 EGF repeats, 3 Notch/Lin repeats. It is highly expressed in the brain, lung, and thymus (CD4-CD8- cells and CD4-CD8+ cells). Lower levels of expression are observed in spleen, bone marrow, spinal cord, eyes, mammary gland, liver, intestine, kidney and heart. Notch-2 regulates a broad spectrum of various cell lineage commitment process, including myogenesis, neurogenesis, gliogenesis and lymphocyte development. Mutation of Notch-2 can cause a rare genetic disorder, Alagille syndrome, with multiple defects in liver, heart and other systems.
Host :
Rat
Research Area :
Epigenetics & Nuclear Signalling, Neurobiology, Stem Cell Biology
more info or order :
Ximbio product webpage
company information
Ximbio
enquiries@ximbio.com
ximbio.com