Anti-MAGE-1 [MA454] | Ximbio 152377 product information

product summary

company name :

Ximbio

product type :

antibody

product name :

Anti-MAGE-1 [MA454]

catalog :

152377

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

4100

reactivity :

human

application :

western blot, immunohistochemistry

more info or order :

Ximbio product webpage

product information

Name :

Anti-MAGE-1 [MA454]

Catalogue Number :

152377

Applications :

IHC WB

Antigen/Gene or Protein Targets :

MAGE-1

Synonyms :

MAGE Family Member A1; Melanoma-Associated Antigen MZ2-E; Cancer/Testis Antigen 1.1; Melanoma Antigen MAGE-1; MAGE-1 Antigen; Antigen MZ2-E; CT1.1; Cancer/Testis Antigen Family 1; MAGE1A

Reactivity :

Human

Relevance :

Human malignant neoplasms carry rejection antigens that are recognized by the patients autologous, tumor directed and specific, cytolytic, CD8+T lymphocyte clones (CTL). An important group of antigens is coded by the MAGE family of genes. It was identified that melanomas and primary glial brain tumors express common melanoma associated antigens (MAAs). Because MAGE-1 is expressed on a significant proportion of human neoplasms of various histological types (melanoma, brain tumors of glial origin, neuroblastoma, non-small cell lung cancer, breast, gastric, colorectal, ovarian, renal cell carcinomas) and not on normal tissues, the encoded antigen may serve as a marker of early detection and target for cancer immunotherapy.

Host :

Mouse

Subclass :

IgG1

Research Area :

Cancer, Cell Type or Organelle Marker

more info or order :

Ximbio product webpage