product summary
company name :
Ximbio
product type :
antibody
product name :
Anti-ASPP1 [LX011]
catalog :
152351
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
23368
reactivity :
human, mouse
application :
western blot, immunoprecipitation
more info or order :
product information
Name :
Anti-ASPP1 [LX011]
Catalogue Number :
152351
Applications :
IP WB
Antigen/Gene or Protein Targets :
ASPP1
Reactivity :
Human, Mouse and Rabbit
Relevance :
The apoptosis stimulating proteins of p53 (ASPP) family consists of three members, ASPP1, ASPP2 and iASPP. They bind to proteins that are key players in controlling apoptosis (p53, Bcl-2 and RelA/p65) and cell growth (APCL, PP1). So far, the best-known function of the ASPP family members is their ability to regulate the apoptotic function of p53 and its family members, p63 and p73. Biochemical and genetic evidence has shown that ASPP1 and ASPP2 activate, whereas iASPP inhibits, the apoptotic but not the cell-cycle arrest function of p53.
Host :
Mouse
Research Area :
Apoptosis and Programmed Cell Death, Cancer, Stem Cell Biology
more info or order :
company information
Ximbio
enquiries@ximbio.com
ximbio.comproduct type
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