Anti-ERCC5 [1XPG-1B5] | Ximbio 152345 product information

product summary

company name :

Ximbio

product type :

antibody

product name :

Anti-ERCC5 [1XPG-1B5]

catalog :

152345

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

1XPG-1B5

reactivity :

human

application :

western blot, ELISA, immunocytochemistry

more info or order :

Ximbio product webpage

product information

Name :

Anti-ERCC5 [1XPG-1B5]

Catalogue Number :

152345

Applications :

ELISA IF WB

Antigen/Gene or Protein Targets :

XPG (Xeroderma pigmentosum group G)

Relevance :

ERCC5 or XPG is a single-strand specific DNA endonuclease that makes the 3' incision in DNA excision repair following UV-induced damage. The protein may also function in other cellular processes, including RNA polymerase II transcription, and transcription-coupled DNA repair. Mutations cause xeroderma pigmentosum complementation group G (XP-G), which is also referred to as xeroderma pigmentosum VII (XP7), a skin disorder characterized by hypersensitivity to UV light and increased susceptibility for skin cancer development following UV exposure. Some patients also develop Cockayne syndrome.

Host :

Mouse

Immunogen :

KKRRKLRRARGRKRKT

Subclass :

IgG1 kappa

Research Area :

DNA Damage and Repair, Epigenetics & Nuclear Signalling

Notes :

Available in 100ul unit

more info or order :

Ximbio product webpage