product summary
company name :
Ximbio
product type :
antibody
product name :
Anti-XPA [1XPA-1E11]
catalog :
152340
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
1XPA-1E11
reactivity :
human
application :
western blot, ELISA, immunocytochemistry
more info or order :
Ximbio product webpage
product information
Name :
Anti-XPA [1XPA-1E11]
Catalogue Number :
152340
Applications :
ELISA IF WB
Antigen/Gene or Protein Targets :
XPA (Xeroderma pigmentosum group A)
Relevance :
Xeroderma pigmentosum group A (XPA) is a zinc finger protein involved in DNA excision repair. The encoded protein is part of the NER (nucleotide excision repair) complex, which is responsible for repair of UV radiation-induced photoproducts and DNA adducts induced by chemical carcinogens. XPA initiates repair by binding to damaged sites with various affinities, depending on the photoproduct and the transcriptional state of the region. Mutations in XPA are associated with xeroderma pigmentosum complementation group A, a rare human autosomal recessive disease characterized by solar sensitivity and high predisposition for developing cancers on areas exposed to sunlight.
Host :
Mouse
Immunogen :
HQHEYGPEENLEDDMYRKT
Subclass :
IgG1 kappa
Research Area :
DNA Damage and Repair, Epigenetics & Nuclear Signalling
Notes :
Available in 100ul unit
more info or order :
Ximbio product webpage
company information
Ximbio
enquiries@ximbio.com
ximbio.com