product summary
company name :
Ximbio
product type :
antibody
product name :
Anti-UL48 [2GV-4]
catalog :
152338
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
2GV-4
reactivity :
human
application :
western blot, ELISA, immunocytochemistry
more info or order :
Ximbio product webpage
product information
Name :
Anti-UL48 [2GV-4]
Catalogue Number :
152338
Applications :
ELISA IF WB
Antigen/Gene or Protein Targets :
VP16
Reactivity :
Virus
Relevance :
UL48 (Herpes virus VP16) activates expression of immediate early (IE) genes in virally-infected cells. It acts as a key activator of lytic infection by initiating the lytic program through the assembly of the transcriptional regulatory VP16-induced complex composed of VP16 and two cellular factors, HCFC1 and POU2F 1. VP16-induced complex represents a regulatory switch: when it is on, it promotes IE-gene expression and thus lytic infection, and when it is off, it limits IE-gene transcription favoring latent infection. UL48 may play a role in the aggregation of tegument proteins around nucleocapsids during virus morphogenesis.
Host :
Mouse
Immunogen :
Recomb prot (411-490)
Subclass :
IgG1 kappa
Research Area :
Cell Signaling & Signal Transduction, Epigenetics & Nuclear Signalling, Gene Expression, Virology
Notes :
Available in 100ul unit
more info or order :
Ximbio product webpage
company information
Ximbio
enquiries@ximbio.com
ximbio.com