Anti-Tdg [1SJ-1F5] | Ximbio 152318 product information

product summary

company name :

Ximbio

product type :

antibody

product name :

Anti-Tdg [1SJ-1F5]

catalog :

152318

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

1SJ-1F5

reactivity :

human

application :

western blot, ELISA, immunocytochemistry

more info or order :

Ximbio product webpage

product information

Name :

Anti-Tdg [1SJ-1F5]

Catalogue Number :

152318

Applications :

ELISA IF WB

Antigen/Gene or Protein Targets :

TDG (Thymine DNA glycosylase)

Relevance :

Thymine DNA glycosylase (TDG) is an enzyme that corrects G/T mispairs to G/C pairs that are formed in the DNA of higher eukaryotes by the hydrolytic deamination of 5-methylcytosine to thymine. TDG is capable of hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of the DNA and a mispaired thymine. In addition to the G/T, TDG can remove thymine also from C/T and T/T mispairs in the order G/T >> C/T > T/T. It has no detectable activity on apyrimidinic sites and does not catalyze the removal of thymine from A/T pairs or from single-stranded DNA. It can also remove uracil and 5-bromouracil from mispairs with guanine.

Host :

Mouse

Immunogen :

Recomb prot (32-421)

Subclass :

IgG2b kappa

Research Area :

Epigenetics & Nuclear Signalling

Notes :

Available in 100ul unit

more info or order :

Ximbio product webpage