Anti-TBP [5TF1-2C1] | Ximbio 152317 product information

product summary

company name :

Ximbio

product type :

antibody

product name :

Anti-TBP [5TF1-2C1]

catalog :

152317

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

5TF1-2C1

reactivity :

human

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry

more info or order :

Ximbio product webpage

product information

Name :

Anti-TBP [5TF1-2C1]

Catalogue Number :

152317

Applications :

ELISA IHC IF WB

Antigen/Gene or Protein Targets :

TBP

Relevance :

TATA-binding protein (TBP) is a general transcription factor that functions at the core of the DNA-binding multiprotein factor TFIID. Binding of TFIID to the TATA box is the initial transcriptional step of the pre-initiation complex (PIC), playing a role in the activation of eukaryotic genes transcribed by RNA polymerase II. Defects in TBP are the cause of spinocerebellar ataxia type 17 (SCA17). The molecular defect in SCA17 is the expansion of a CAG repeat in the coding region of TBP. Longer expansions result in earlier onset and more severe clinical manifestations of the disease.

Host :

Mouse

Immunogen :

Recomb prot

Subclass :

IgG2b kappa

Research Area :

Epigenetics & Nuclear Signalling, Gene Expression

Notes :

Available in 100ul unit

more info or order :

Ximbio product webpage