Anti-TAF4 [20TA-1B12] | Ximbio 152307 product information

product summary

company name :

Ximbio

product type :

antibody

product name :

Anti-TAF4 [20TA-1B12]

catalog :

152307

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

6874

reactivity :

human, mouse

application :

western blot, ELISA, immunohistochemistry, immunoprecipitation

more info or order :

Ximbio product webpage

product information

Name :

Anti-TAF4 [20TA-1B12]

Catalogue Number :

152307

Applications :

ELISA IHC IP WB

Antigen/Gene or Protein Targets :

TAF4 (formerly TAFII135)

Reactivity :

Human and Mouse

Relevance :

TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. TAF4 is one of the larger subunits of TFIID that has been shown to potentiate transcriptional activation by retinoic acid, thyroid hormone and vitamin D3 receptors. In addition, this subunit interacts with the transcription factor CREB, which has a glutamine-rich activation domain, and binds to other proteins containing glutamine-rich regions. Aberrant binding to this subunit by proteins with expanded polyglutamine regions has been suggested as one of the pathogenetic mechanisms underlying a group of neurodegenerative disorders referred to as polyglutamine diseases.

Host :

Mouse

Immunogen :

Recombinant TAF4 protein KNKLKEPGGGSFRDDDDINDVA. Epitope localised between amino acids 815-836

Subclass :

IgG1 kappa

Research Area :

Epigenetics & Nuclear Signalling

Notes :

Available in 100ul units Recommended dilution: 1/500-1/5000

more info or order :

Ximbio product webpage