product summary
company name :
Ximbio
product type :
antibody
product name :
Anti-SRSF2 [1SC-4F11]
catalog :
152289
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
9912
reactivity :
human, mouse
application :
western blot, ELISA, immunocytochemistry
more info or order :
product information
Name :
Anti-SRSF2 [1SC-4F11]
Catalogue Number :
152289
Applications :
ELISA IF WB
Antigen/Gene or Protein Targets :
SC35 (Splicing factor R/S-rich 2. SRSF2)
Reactivity :
Human and Mouse
Relevance :
SC35 is necessary for the splicing of pre-mRNA. It is required for formation of the earliest ATP-dependent splicing complex and interacts with spliceosomal components bound to both the 5'- and 3'-splice sites during spliceosome assembly. It also is required for ATP-dependent interactions of both U1 and U2 snRNPs with pre-mRNA. SC35 interacts with other spliceosomal components, via the RS domains, to form a bridge between the 5'- and 3'-splice site binding components, U1 snRNP and U2AF.
Host :
Mouse
Immunogen :
Synthetic peptide coupled to Ovalbumin (C)-KSPPKSPEEEGAVSS corresponding to aa 207-221 of human SC35
Subclass :
IgG1 kappa
Research Area :
Epigenetics & Nuclear Signalling
Notes :
Recommend dilutions: 1/500 - 1/5000. Available in 100ul units.
more info or order :
company information
Ximbio
enquiries@ximbio.com
ximbio.com