product summary
company name :
Ximbio
product type :
antibody
product name :
Anti-POLR2E [2PB-4H7]
catalog :
152278
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
2PB-4H7
reactivity :
human
application :
western blot, ELISA, immunocytochemistry
more info or order :
product information
Name :
Anti-POLR2E [2PB-4H7]
Catalogue Number :
152278
Applications :
ELISA IF WB
Antigen/Gene or Protein Targets :
RNA Polymerase B Subunit hRPB5
Relevance :
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. Pol II is the central component of the basal RNA polymerase II transcription machinery. Pols are composed of mobile elements that move relative to each other. In Pol II, POLR2E/RPB5 is part of the lower jaw surrounding the central large cleft and thought to grab the incoming DNA template. Seems to be the major component in this process.
Host :
Mouse
Immunogen :
Recombinant human hRPB5 protein.
Subclass :
IgG1 kappa
Research Area :
Epigenetics & Nuclear Signalling
Notes :
Available in 100ul unit as ascites. The hRPB5 protein is present in RNA polymerases I, II and III.
more info or order :
company information
Ximbio
enquiries@ximbio.com
ximbio.com