Anti-PGR [PR-6A] | Ximbio 152267 product information

product summary

company name :

Ximbio

product type :

antibody

product name :

Anti-PGR [PR-6A]

catalog :

152267

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

5241

reactivity :

human, chicken

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry

more info or order :

Ximbio product webpage

product information

Name :

Anti-PGR [PR-6A]

Catalogue Number :

152267

Applications :

ELISA IHC IF WB

Antigen/Gene or Protein Targets :

Progesterone receptor

Reactivity :

Chicken and Human

Relevance :

The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Progesterone receptor isoform B (PRB) is involved activation of c-SRC/MAPK signaling on hormone stimulation. Isoform A: inactive in stimulating c-Src/MAPK signaling on hormone stimulation. Isoform 4: Increases mitochondrial membrane potential and cellular respiration upon stimulation by progesterone.

Host :

Mouse

Immunogen :

AGMVKPLLFHKK

Subclass :

IgG2a kappa

Research Area :

Epigenetics & Nuclear Signalling

Notes :

Available in 100ul unit The peptide used as immunogen for this product corresponds to the C terminal sequence of the human PR (end of E region – Hormone binding domain) : 922 AGMVKPLLFHKK 933. This antibody cross reacts with chicken PR and should also work on rabbit PR since the sequence is 100 % conserved between human, chicken and rabbit.

more info or order :

Ximbio product webpage