product summary
company name :
Ximbio
product type :
antibody
product name :
Anti-MMP11 [5ST-4A9]
catalog :
152251
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
4320
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry
more info or order :
product information
Name :
Anti-MMP11 [5ST-4A9]
Catalogue Number :
152251
Applications :
ELISA IHC IF WB
Antigen/Gene or Protein Targets :
MMP11 / Stromelysin-3
Reactivity :
Human
Relevance :
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the enzyme encoded by this gene is activated intracellularly by furin within the constitutive secretory pathway. Also in contrast to other MMP's, MMP11 cleaves alpha 1-proteinase inhibitor but weakly degrades structural proteins of the extracellular matrix.
Host :
Mouse
Immunogen :
Recomb prot
Subclass :
IgG1 kappa
Research Area :
Adhesion, Cancer, Cardiovascular, Epigenetics & Nuclear Signalling
Notes :
Available in 100ul unit
more info or order :
company information
Ximbio
enquiries@ximbio.com
ximbio.com