product summary
company name :
Ximbio
product type :
antibody
product name :
Anti-MNAT1 [35TF2-2D3]
catalog :
152248
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
4331
reactivity :
human
application :
western blot, ELISA, immunocytochemistry
more info or order :
product information
Name :
Anti-MNAT1 [35TF2-2D3]
Catalogue Number :
152248
Applications :
ELISA IF WB
Antigen/Gene or Protein Targets :
MAT1-p32 / MNAT1
Reactivity :
Human
Relevance :
The protein named Arylamine N-acetyltransferase 1 or alternatively Arylamide acetylase 1, Monomorphic arylamine N-acetyltransferase (MNAT), or N-acetyltransferase type 1 (NAT-1) is a detoxifying enzyme that helps to metabolize drugs and other xenobiotics. NAT1 also functions in folate catabolism. Interestingly, NAT1 is one of two N-acetyltransferase isozymes in humans that also catalyze both N-acetylation (usually deactivation) and O-acetylation (usually activation) of aromatic and heterocyclic amine carcinogens. Epidemiological studies suggest that the NAT1 and NAT2 acetylation polymorphisms modify risk of developing urinary bladder, colorectal, breast, head and neck, lung, and possibly prostate cancers. NAT1 is expressed principally in the liver but can also be found expressed in kidney, lung and trachea, with minor expression seen in most other tissues as well.
Host :
Mouse
Immunogen :
ALQDAFSGLFWQP
Subclass :
IgG1 kappa
Research Area :
Cell Cycle, Epigenetics & Nuclear Signalling
Notes :
Available in 100ul unit
more info or order :
company information
Ximbio
enquiries@ximbio.com
ximbio.com