Anti-HTT [1HU-4C8] | Ximbio 152241 product information

product summary

company name :

Ximbio

product type :

antibody

product name :

Anti-HTT [1HU-4C8]

catalog :

152241

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

3064

reactivity :

human, mouse, rat

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry

more info or order :

Ximbio product webpage

product information

Name :

Anti-HTT [1HU-4C8]

Catalogue Number :

152241

Applications :

ELISA IHC IF WB

Antigen/Gene or Protein Targets :

Huntingtin

Reactivity :

Human, Mouse, Primate and Rat

Relevance :

Defects in HTT are the cause of Huntington disease (HD) [MIM:143100]. HD is an autosomal dominant neurodegenerative disorder characterized by involuntary movements (chorea), general motor impairment, psychiatric disorders and dementia. Onset of the disease occurs usually in the third or fourth decade of life and symptoms progressively worsen leading to death in 10 to 20 years. Onset and clinical course depend on the degree of poly-Gln repeat expansion, longer expansions resulting in earlier onset and more severe clinical manifestations. HD affects 1 in 10,000 individuals of European origin. Neuropathology of Huntington disease displays a distinctive pattern with loss of neurons, especially in the caudate and putamen (striatum).

Host :

Mouse

Immunogen :

Recomb prot (181-810)

Subclass :

IgG1 kappa

Research Area :

Neurobiology

Notes :

Available in 100ul unit

more info or order :

Ximbio product webpage